The effects of G-spot stimulation when using the penis or a G-spot vibrator may be enhanced by additionally stimulating other erogenous zones on a woman's body, such as the clitoris or vulva as a whole. The potential risks include sexual dysfunction, infection, altered sensation, dyspareunia , adhesions and scarring. They acquired the largest sample size of women to date — 1, — who are pairs of twins, and found that the twins did not report a similar G-spot in their questionnaires. After numbing the area with a local anesthetic, human engineered collagen is then injected directly under the mucosa in the area the G-spot is concluded to be in. The surveys found that a majority of women believe a G-spot actually exists, although not all of the women who believed in it were able to locate it. On this basis, Masters and Johnson argued that clitoral stimulation is the source of both kinds of orgasms,   reasoning that the clitoris is stimulated during penetration by friction against its hood. Modern scientific hypotheses linking G-spot sensitivity with female ejaculation led to the idea that non-urine female ejaculate may originate from the Skene's gland, with the Skene's gland and male prostate acting similarly in terms of prostate-specific antigen and prostate-specific acid phosphatase studies,   which led to a trend of calling the Skene's glands the female prostate. Several variables were associated with this perceived existence of female ejaculation. One common sex toy is the specially-designed G-spot vibrator , which is a phallus -like vibrator that has a curved tip and attempts to make G-spot stimulation easy.
It's a region, it's a convergence of many different structures. The main researcher of the studies, Australian urologist Helen O'Connell, asserts that this interconnected relationship is the physiological explanation for the conjectured G-spot and experience of vaginal orgasms, taking into account the stimulation of the internal parts of the clitoris during vaginal penetration. When the research team asked several women to stimulate themselves in a functional magnetic resonance fMRI machine, brain scans showed stimulating the clitoris, vagina and cervix lit up distinct areas of the women's sensory cortex, which means the brain registered distinct feelings between stimulating the clitoris, the cervix and the vaginal wall — where the G-spot is reported to be. The research, headed by Tim Spector, documents a year study of the twins, identical and non-identical. Upon studying women's sexual response cycle to different stimulation, they observed that both clitoral and vaginal orgasms had the same stages of physical response, and found that the majority of their subjects could only achieve clitoral orgasms, while a minority achieved vaginal orgasms. On this basis, Masters and Johnson argued that clitoral stimulation is the source of both kinds of orgasms,   reasoning that the clitoris is stimulated during penetration by friction against its hood. G-spot amplification is performed by attempting to locate the G-spot and noting measurements for future reference. He stated, "Clitoral bulbs is an incorrect term from an embryological and anatomical viewpoint, in fact the bulbs do not develop from the phallus, and they do not belong to the clitoris. The potential risks include sexual dysfunction, infection, altered sensation, dyspareunia , adhesions and scarring. Methods included a midwife rubbing the walls of the vagina or insertion of the penis or penis-shaped objects into the vagina. Furthermore, radiographic studies have been unable to demonstrate a unique entity, other than the clitoris, whose direct stimulation leads to vaginal orgasm. They assert that since the front wall of the vagina is inextricably linked with the internal parts of the clitoris, stimulating the vagina without activating the clitoris may be next to impossible. One common sex toy is the specially-designed G-spot vibrator , which is a phallus -like vibrator that has a curved tip and attempts to make G-spot stimulation easy. When using a G-spot vibrator, this may be done by manually stimulating the clitoris, including by using the vibrator as a clitoral vibrator , or, if the vibrator is designed for it, by applying it so that it stimulates the head of the clitoris, the rest of the vulva and the vagina simultaneously. Attempts to characterize vaginal innervation have shown some differences in nerve distribution across the vagina, although the findings have not proven to be universally reproducible. Skene's gland and Urethral sponge In , the Federative Committee on Anatomical Terminology accepted female prostate as an accurate term for the Skene's gland, which is believed to be found in the G-spot area along the walls of the urethra. Because female fetal development is the "default" direction of fetal development in the absence of substantial exposure to male hormones and therefore the penis is essentially a clitoris enlarged by such hormones, Kilchevsky believes that there is no evolutionary reason why females would have two separate structures capable of producing orgasms and blames the porn industry and "G-spot promoters" for "encouraging the myth" of a distinct G-spot. However, reliable reports and anecdotal testimonials of the existence of a highly sensitive area in the distal anterior vaginal wall raise the question of whether enough investigative modalities have been implemented in the search of the G-spot. Objective measures have failed to provide strong and consistent evidence for the existence of an anatomical site that could be related to the famed G-spot. Several variables were associated with this perceived existence of female ejaculation. Within this context, various methods were used over the centuries to release "female seed" via vaginal lubrication or female ejaculation as a treatment for suffocation ex semine retento suffocation of the womb , female hysteria or green sickness. Theorized structure Location Two primary methods have been used to define and locate the G-spot as a sensitive area in the vagina: The effects of G-spot stimulation when using the penis or a G-spot vibrator may be enhanced by additionally stimulating other erogenous zones on a woman's body, such as the clitoris or vulva as a whole. While using MRI technology, O'Connell noted a direct relationship between the legs or roots of the clitoris and the erectile tissue of the "clitoral bulbs" and corpora, and the distal urethra and vagina. Modern scientific hypotheses linking G-spot sensitivity with female ejaculation led to the idea that non-urine female ejaculate may originate from the Skene's gland, with the Skene's gland and male prostate acting similarly in terms of prostate-specific antigen and prostate-specific acid phosphatase studies,   which led to a trend of calling the Skene's glands the female prostate. The male prostate is biologically homologous to the Skene's gland;  it has been unofficially called the male G-spot because it can also be used as an erogenous zone. On the basis of this research, they argued that women may be able to achieve vaginal orgasm via stimulation of the G-spot because the highly innervated clitoris is pulled closely to the anterior wall of the vagina when the woman is sexually aroused and during vaginal penetration.
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